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For patients and healthcare professionals, the key takeaway is that while Mounjaro shares many characteristics with GLP-1 receptor agonistsincluding similar side effects, administration route, and clinical indicationsit has a dual mechanism that targets both GIP and GLP-1 receptors

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A future goal is to increase the translational capacity of our approach by identifying direct, predictive links between behavioral profiles and specific human symptoms and outcomes

In patients taking JANUMET XR whose eGFR later falls below 45 mL/min/1.73 m, assess the benefit and risk of continuing therapy